Article 3316

Title of the article



Solovev Vladimir Borisovich, Doctor of biological sciences, professor, sub-department of general biology and biochemistry, Penza State University (40 Krasnaya street, Penza, Russia),
Volodin Roman Nikolaevich, Lecturer, sub-department of physical training, Penza Artillery Engineering Institute (Penza-5, Russia),
Stolyarov Anton Anatolyevich, Head of the laboratory of radioisotope diagnostics, Penza Regional Oncology Center (37A Stroiteley avenue, Penza, Russia),

Index UDK





Background. The purpose of this article is to review the results of modern exper-imental studies of changes in the peptidergic system during physical work. Over for-ty years of studying this problem, many experimental data, originally seeming con-tradictory, today allow us to form a hypothesis of chain activation of the system during systematic physical loads.
Materials and methods. This review presents the results of a wide range of re-searches of levels of regulatory peptides, peptide hormones in blood, animal tissues, as well as the concentration of mRNA of peptides precursors and activities of en-zymes taking part in peptides exchange.
Results. As a result the authors suggest that complex activation of the peptidergic system is an important adaptive mechanism that activates during systematic physical work in highly skilled athletes.
Conclusions. The given scheme shows the predominant adaptive role of the link of the peptidergic system associated with the regulation of the nervous system that allows us to formulate the hypothesis of a “physically trained nervous system”.

Key words

peptidergic system, regulatory peptides, hormones, peptidhydrola¬ses, physical exercise.

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